By clicking on the faculty member's name below, you will find direct links to all of the faculty's websites. If their name does not send you directly to their page, it will set up an email where they can be reached

     

Biochemistry and Molecular Genetics

Molecular Medicine

Microbiology, Immunology, and Tropical Medicine

Mark Allard
Associate Research Professor; Ph.D. 1983, Utah State University. Purification and characterization of synthetic AIDS vaccine (HGP30) and biologically active peptides from thymosin fraction 5; characterization and study of the mechanisms of action of different forms of choline O-acetyltransferase from rat brain.

Mahnaz Badamchian
Associate Research Professor; Ph.D. 1983, Utah State University. Isolation and characterization of thymosins and cholin.

Patricia E. Berg
Associate Professor of Biochemistry & Molecular Biology; Ph.D. 1973, Illinois Institute of Technology.  Role of homeobox genes in breast cancer and leukemial; sickle cell anemia therapy.

Bernard Bouscarel (Program Director)
Associate Research Professor of Medicine and of Biochemistry & Molecular Biology; Ph.D. 1985, D. Sc. 1995, University of Toulouse, France. Signal transduction pathways (calcium, cAMP, and protein kinase C) and carcinogenesis; hormones, bile acids, and hepatobiliary disorders.

Ken Brown
Professor of Biology and Genetics. Role of neurotransmitters and hormones in cell differentiation.

Anne Chiaramello (Lab Rotations Director)
Assistant Professor of Anatomy and Cell Biology; Ph.D. 1990, University of California, San Diego.
Gene regulatory networks and neurodegenerative disorders.

Anamaris M. Colberg-Poley
Professor of Pediatrics, Biochemistry and Molecular Biology; Ph.D. 1980, Pennsylvania State University at Hershey. Regulation of gene expression and protein trafficking of cytomegalovirus.

Nancy Colburn Chief, Laboratory of Cancer Prevention; Chief, Gene Regulation Section, LCP, NCI. Ph.D., University of Wisconsin. Transcriptional and Translational events that drive multistage carcinogenesis and might be targeted for cancer prevention. AP-1 and NFkB dependent transcription. Translation initiation and the regulation of eIF4F. Molecular Targets for Cancer Prevention. Use of Mouse Models for Discovery and validation of molecular targets.

David Derse
Adjunct Profession of Genetics; Ph.D. 1982, State University of New York at Buffalo. Current work focuses on the molecular mechanisms of human T-cell leukemia virus type 1 infection and replication.

Robert Donaldson
Glyoxysomal membrane electron transport.

Sydney W. Fu
Assistant Research Professor; Ph.D. 1994, Peking Union Medical College, M.D. 1989, Xi'an Medical University. Homeobox genes in breast cancer and cancer genetics; bioinfomatics.

David Goldman

Allan L. Goldstein
Professor and Chair of Biochemistry & Molecular Biology; Ph.D. 1964, Rutgers University.  Chemical and biological properties of the thymosins; neuroimmunology; immunodeficiency diseases; cancer; AIDS; aging.

Gordon Hager
Adjunct Professor of Genetics and Pharmacology. Transcriptional regulation and chromatin structure.

Robert Hawley
Professor of Anatomy & Cell Biology; Ph.D. 1984, University of Toronto. Experimental hematology/oncology; gene delivery systems and gene therapy modeling; stem cell and regenerative biology.

Eric P. Hoffman
Professor of Pediatrics and of Biochemistry & Molecular Biology; M.D. 1987, Johns Hopkins University. Molecular basis of inherited muscle and CNS disease utilizing DNA gene chip technology.

Valerie W. Hu (Program Director)
Professor Ph.D. Caltech 1978, California Institute of Technology. Genomic, epigenetic, metabolomic, and bioinformatic analyses of autism spectrum disorders; biomarkers; mechanistic pathways.

Diana Johnson
Population genetics and molecular evolution.

Fatah Kashanchi
Associate Professor of Biochemistry & Molecular Biology; Ph.D. 1991, University of Kansas. Molecular pathogenesis of AIDS and HTL; cell-cycle associated events related to host cell and human retroviruses, including HIV-1 and HTLV-1; genomics and proteomic analysis of radiation effects.

Andrei Komarov
Associate Research Professor; M.D. 1984, Russian State Medical University (formerly Moscow 2nd Medical Institute); Ph.D. 1988, Inst. Of Chemical Physics, USSR Academy of Sciences, Moscow. Nitric oxide: biochemistry and detection; biomedical applications of electron paramagnetic resonance spectroscopy.

Jay H. Kramer
Associate Research Professor; 1982, Lehigh University. Oxidative injury, free-radical detection, and dysfunction during myocardial ischemia/reperfusion; oxidative stress during dietary Mg-deficiency and iron overload; antioxidant therapy.

Ajit Kumar
Professor of Biochemistry & Molecular Biology; Ph.D. 1968, University of Chicago. Regulation of viral gene transactivation; role of cellular factors; RNA protein interactions.

Stephan Ladisch
Professor of Pediatrics; M.D. 1973, University of Pennsylvania.  Tumor cell ganglioside metabolism, tumor progression, and immuno suppression.

Raj Lakshman
Coronary heart disease; lipids; metabolic and genetic obesity; hepatoxins; gene regulation and expression; retinoids.

Patricia S. Latham
Associate Professor of Pathology; M.D. 1972, University of Southern California.  Gene regulation and cytokine response of tumoricidal monocytes.

Tim McCaffrey
Professor of Biochemistry & Molecular Biology; Ph.D. 1985, Purdue University. Cardiovascular and stem cell genomics.

I. Tong Mak
Associate Research Professor; Ph.D. 1982, University of Wisconsin-Madison. Free radical pathobiology in cardiovascular cells; Antioxidant drug mechanisms and therapy; Role of the lysosome in iron overload; AZT toxicity; Mg-deficiency-induced inflammation.

Phillipe Marmillot
Alcohol consumption; alcoholic liver disease; cardiovascular disease; small GTP-binding proteins, annexins; protein trafficking.

Carl R. Merril
Adjunct Professor of Genetics and Biochemistry; M.D. 1962 Georgetown University School of Medicine, Interactions of bacterial viruses with mammalian systems; protein detection; mitochondrial deletion mutations; human genomic variations; aging.

Sally A. Moody
Professor of Anatomy & Cell Biology; Ph.D. 1981, University of Florida. Molecular and cellular determination of neuronal phenotypes; regulation of neurotransmitters in the developing retina.

JoAnne Natale
Assistant Professor of Pediatrics; Ph.D 1988 University of Michigan; M.D. 1993, Michigan State University. Mechanism of injury-induced neuronal death and modification of antioxidant response; neurodevelopmental deficits in Neurofibromatosis.

Frances P. Noonan
Professor of Environmental and Occupational Health; Ph.D. 1977, University of Queensland Australia.  The role of ultraviolet radiation in melanoma and non-melanoma skin cancer.

Stephen J. O'Brien
Chief of the Laboratory of Genomic Diversity at the National Cancer Institute in Frederick, Maryland, USA.  Principal research focus involves the discovery and characterization of human genes that regulate response to infectious diseases, particularly AIDS, hepatitis and cancer. He also studies the evolution of mammalian genome organization though studies of comparative genomics of the domestic cat, their wild felid relatives, and their infectious disease agents.

Randall K. Packer
Professor of Biology; Ph.D. 1971, Pennsylvania State. Electrolyte and acid-base balance; kidney function.

Thomas Parsons
Chief Scientist, Armed Forces DNA Identification Laboratory, Armed Forces Institute of Pathology; Ph.D in Biochemistry,1989, University of Washington. Characterization of genetics systems for human forensic identification, molecular evolution and genomics of mitochondrial DNA, ancient DNA extraction and analysis, statistical and population genetic interpretation of forensic DNA data, bioinformatics, robotic, high throughput DNA typing.

Steven R. Patierno
Professor of Pharmacology & Physiology; Ph.D. 1985, University of Texas. Cellular and molecular mechanisms of carcinogenesis; gene expression in tumor cells; metal toxicology; control of invasion and metastasis.

Joseph Pizone
Cellular differentiation; endocrinology; metabolism; tumor; translational research.

Marcos Rojkind
Research Professor; MD 1962, National University of Mexico & Ph.D. 1970, National Polytechnical Institute of Mexico.

Mary C. Rose
Associate Research Professor of Pediatrics and of Biochemistry & Molecular Biology; Ph.D. 1970, Case Western Reserve University. Mucin glycoproteins in airway diseases and cystic fibrosis; regulation of MUC5 gene.

Rita Teresa Roy
Bioinformatics; distance learning.

Pam Schwartzberg
Senior Research Investigator, NHGRI; MD, Ph.D.1992, Columbia University. T lymphocyte signal transduction, T lymphoctye activation and development.

Courtney Smith
Associate Professor of Biology; Ph.D. 1985, UCLA. Origins and evolution of the vertebrate immune system in sea urchins.

Margaret Sutherland
Assistant Professor of Pediatrics, Ph.D. 1993, Open University, Cambridge, England.  Transgenic approaches to molecular neuroscience, function of glutamate transporters and potassium channels.

Frank J. Turano
Associate Professor of Biology and Genetics; Ph.D. 1986, Miami University, Ohio. Evolution and function of glutamate receptors and stress response to abiotic and biotic factors.

Jack Vanderhoek
Professor; Ph.D. 1966, Massachusetts Institute of Technology. Regulation of eicosanoid metabolism by natural and pharmacological agents.

Glenn A. Walker
Techniques in teaching biochemistry for graduate students and medical students.

Thomas Wellems
M.D., Ph.D. Head, Malaria Genetics Section; Acting Chief, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health.

Jurgen Weiss
Molecular Signaling Section, Chief; Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health; Ph. D. 1987 (Pharmacology), Johann Wolfgang-Goethe University, Germany. G protein-coupled receptors (GPCRs): Molecular basis of activation and function. Generation and analysis of muscarinic acetylcholine receptor knockout mice

Irene Zohn
Department of Neuroscience, Children's National Medical Center. PhD from UNC-Chapel Hill Our goal is to understand the genes and signal transduction pathways required for morphogenesis of the vertebrate embryo. We use a forward genetic approach in the mouse to identify novel genes required for two early morphogenic events: gastrulation and neural tube closure. From this screen we have identified a number of mouse mutants. The current focus of the lab is on the characterization of the genetic and developmental defects in two ENU-derived mutant mouse lines that display defects in gastrulation and neural tube closure: droopy eye (drey) and openmind (opm). We use a variety of techniques to characterize the developmental defects in these mutant mice strains including, embryology, molecular biology, biochemistry, genetics and genetic engineering.

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Patricia E. Berg
Associate Professor of Biochemistry & Molecular Biology; Ph.D. 1973, Illinois Institute of Technology.  Molecular Mechanisms of Breast Cancer Progression.

Bernard Bouscarel (Program Director)
Associate Research Professor of Medicine and of Biochemistry & Molecular Biology; Ph.D. 1985, D. Sc. 1995, University of Toulouse, France. Signal transduction pathways (calcium, cAMP, and protein kinase C) and carcinogenesis; hormones, bile acids, and hepatobiliary disorders.

Susan CeryakAssociate Research Professor of Pharmacology & Physiology; Ph.D. 1994, George Washington University. Signaling pathways involved in cell cycle regulation and dysregulation in cancer

Vincent A. Chiappinelli
The Ralph E. Loewi Professor and Chair of Pharmacology & Physiology; Ph.D. 1977, University of Connecticut. Patch-clamp electrophysiology; functional and pharmacological studies of nicotinic receptors and presynaptic nerve terminals.

Anne Chiaramello (Lab Rotations Director)
Assistant Professor of Anatomy and Cell Biology; Ph.D. 1990, University of California, San Diego.
Gene regulatory networks and neurodegenerative disorders.

Edward C. DeFabo
Professor of Environmental and Occupational Health; Ph.D. 1974, George Washington University. UV radiation carcinogenesis and UV effects on cellular immunity.

Stephen Dopkins
Assistant Professor of Psychology; Ph.D. 1988, Columbia University. Neuropsychology; memory.

Vittorio Gallo
Professor of Pediatrics and Pharmacology & Physiology; Ph.D., 1979 University of Rome, Italy. Neurogenesis and gliogenesis; oligodendrocyte development and myelination; glial signaling; regulation of glial ionic channels during brain development.

Allan L. Goldstein
Professor and Chair of Biochemistry & Molecular Biology; Ph.D. 1964, Rutgers University.  Chemical and biological properties of the thymosins; neuroimmunology; immunodeficiency diseases; cancer; AIDS; aging.

Tim Hales
Professor of Pharmacology & Physiology, Ph.D. 1990, University of Dundee.  Molecular mechanism of action of general anesthetics and opioids.

Yetrib Hathout
Assistant Professor of Pediatrics; Ph.D. 1992, University of Burgundy, France. Proteomics and mass spectrometry applications to study the pathophysiology of human diseases (cancer and neurodegenerative diseases).

Robert Hawley
Professor of Anatomy & Cell Biology; Ph.D. 1984, University of Toronto. Experimental hematology/oncology; gene delivery systems and gene therapy modeling; stem cell and regenerative biology.

Tarik Haydar
Assistant Professor of Pediatrics and Pharmacology & Physiology; Ph.D. 1997, University of Maryland. Cell and molecular analysis of neural stem cell proliferation and differentiation in the embryonic cerebral cortex with an emphasis on multiphoton imaging.

Eric P. Hoffman
Professor of Pediatrics and of Biochemistry & Molecular Biology; M.D. 1987, Johns Hopkins University. Molecular basis of inherited muscle and CNS disease utilizing DNA gene chip technology.

Valerie W. Hu
Associate Professor of Biochemistry and Molecular Biology and of Genetics; Ph.D. 1978, California Institute of Technology. Role of gap junctions in proliferation of smooth muscle and endothelial cells and in vascular disease; effects of B-radiation on cell cycle, proliferation and apoptosis.

Fatah Kashanchi
Associate Professor of Biochemistry & Molecular Biology. Genomics and proteomics of HIV-1 and HTLV-1 infected cells.

Katherine A. Kennedy
Professor of Pharmacology & Physiology; Ph.D. 1977, University of Iowa.  Role of bio-trans-formation in drug activity and toxicity; role of microenvironments in tumor-cell sensitivity to anticancer agents; molecular actions of antitumor drugs.

Ewen F. Kirkness
Associate Professor of Pharmacology & Physiology (at TIGR); Ph.D. 1985, Leeds ( England).
cDNA libraries; receptors; ion channels; recombinant expression; structure; serotonin; GABA.

Janette Krum
Associate Professor of Anatomy & Cell Biology; Ph.D. 1987, George Washington University. Role of astrocytes in CNS repair; role of VEGF in CNS development and repair.

Ajit Kumar
Professor of Biochemistry & Molecular Biology; Ph.D. 1968, University of Chicago. RNA-protein interaction; transactivation of HIV gene expression.

Stephan Ladisch
Professor of Pediatrics; M.D. 1973, University of Pennsylvania.  Tumor cell ganglioside metabolism, tumor progression, and immuno suppression.

Patricia S. Latham
Associate Professor of Pathology; M.D. 1972, University of Southern California.  Gene regulation and cytokine response of tumoricidal monocytes.

Paolo Lecchi
Associate Research Professor of Pharmacology & Physiology. Biomedical applications of mass spectrometry; proteomics.

Norman H. Lee
Associate Professor of Pharmacology & Physiology; Ph.D. 1990, University of Maryland. Studying mRNA regulation and global patterns of gene expression with DNA microarrays.

Craig Linebaugh

Tobey McDonald
Associate Professor of Pediatrics; M.D. 1991, Cornell University. Regulation of tumor metastasis and angiogenesis by receptor tyrosine kinase signaling in childhood brain tumors.

H. George Mandel
Professor of Pharmacology & Physiology, Ph.D. 1949, Yale University.  Growth inhibitory agents and cancer chemotherapy; nucleic acid anti-metabolites and cancer drug metabolism; mechanisms and prevention of carcinogenesis.

Tim McCaffery
Professor of Biochemistry & Molecular Biology; Ph.D. 1985, Purdue University. Cardiovascular and stem cell genomics.

David Mendelowitz
Professor of Pharmacology & Physiology, Ph.D. 1989, University of Washington.  Electrophysiology and morphology of cardiac vagal neurons and cardiorespiratory neurons.

Sally A. Moody
Professor of Anatomy & Cell Biology; Ph.D. 1981, University of Florida. Molecular and cellular determination of neuronal phenotypes; regulation of neurotransmitters in the developing retina.

JoAnne Natale
Assistant Professor of Pediatrics; Ph.D 1988, University of Michigan; M.D. 1993, Michigan State University. Mechanism of injury-induced neuronal death and modification of antioxidant response; neurodevelopmental deficits in Neurofibromatosis.

Jenae Neiderhauser
Associate Professor of Psychiatry & Behavioral Sciences; Ph.D. 1994, University of Pennsylvania. Interplay between genes and family environment.

Frances P. Noonan
Professor of Environmental and Occupational Health; Ph.D. 1977, University of Queensland Australia.  The role of ultraviolet radiation in melanoma and non-melanoma skin cancer.

Travis O’Brien
Associate Research Professor of Pharmacology & Physiology.

Randall K. Packer
Professor of Biology; Ph.D. 1971, Pennsylvania State. Electrolyte and acid-base balance; kidney function.

Steven R. Patierno
Professor of Pharmacology & Physiology, Ph.D. 1985, University of Texas. Cellular and molecular mechanisms of carcinogenesis; gene expression in tumor cells; metal toxicology; control of invasion and metastasis.

David C. Perry
Professor of Pharmacology & Physiology, Ph.D. 1981, University of California, San Francisco.  Nicotinic receptor subtypes; neurotransmitter receptor localization and regulation; intracellular calcium.

Kenna D. Peusner
Professor of Anatomy & Cell Biology; Ph.D. 1974, Harvard University. Role of synaptic transmission in the development of the central vestibular neural circuit.

John W. Philbeck
Assistant Professor of Psychology; Ph.D. 1997, University of California, Santa Barbara. Human visual space perception and navigation; cognitive neuroscience.

Mary C. Rose
Associate Research Professor of Pediatrics and of Biochemistry & Molecular Biology; Ph.D. 1970, Case Western Reserve University. Mucin glycoproteins in airway diseases and cystic fibrosis; regulation of MUC5 gene.

Jeffrey M. Rosenstein
Professor of Anatomy and of Neurological Surgery; Ph.D. 1976, Pennsylvania State University.
Neural transplantation; neurovascular development; neuro-oncology.

Lawrence A. Rothblat
Professor of Psychology and of Anatomy & Cell Biology; Ph.D. 1968, University of Connecticut.
Psychobiology of learning and memory; recovery of function in CNS.

Narine Sarvazyan
Associate Professor of Pharmacology & Physiology; Ph.D. 1991, National Academy of Sciences of Armenia. Cellular origins of ectopic arrhythmias, ischemia-reperfusion injury, cell-to-cell coupling, targeted stem cell differentiation.

Eva M. Sorenson
Associate Research Professor of Pharmacology & Physiology, Ph.D. 1990, St. Louis University. Nicotinic cholinergic neurotransmission in the central nervous system; localization and pharmacology of nicotinic receptors.

Mary Ann Stepp
Associate Professor of Anatomy & Cell Biology and of Opthalmology; Ph.D. 1986, Boston University.  Cell-cell and cell-substrate interaction; integrins; wound healing; re-epithelization.

Margaret Sutherland
Assistant Professor of Pediatrics, Ph.D. 1993, Open University, Cambridge, England.  Transgenic approaches to molecular neuroscience, function of glutamate transporters and potassium channels.

Linda L. Werling (Director of the Institute for Biomedical Sciences)
Professor of Pharmacology & Physiology, Ph.D. 1983, Duke University.  Role of sigma, PCP, and nicotine receptors in brain function; regulation of catecholamine release in brain; receptor-mediated regulation of transporters.

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